leadXpro

Laboratory Technician Protein Expression and Purification

 
leadXpro

Published
Closing Date
WorkplaceVilligen, Zurich region, Switzerland
Category
Position

Founded in 2015, leadXpro AG is an established lead compound discovery company focusing on membrane protein drug targets such as GPCR’s, ion-channels and transporters. We are committed to the application of biophysical and structure-based methods for the discovery and optimization of next generation medicines. We capitalize on our knowledge and experience in membrane protein structural biology facilitated by co-location with the synchrotron (Swiss Light Source - SLS), the Free Electron Laser (SwissFEL) at the PSI. Furthermore, we collaborate with the cryo-EM facility at the University of Basel. The job at leadXpro is an excellent opportunity to join a young and exciting company engaged in cutting edge applied research. leadXpro is located at the PARK INNOVAARE, 5234 Villigen, Switzerland. For more information, please visit: ?url=http%3A%2F%2Fleadxpro.com&module=jobs&id=2969" target="_blank" rel="nofollow">http://leadxpro.com

Description

leadXpro is urgently seeking a highly motivated and enthusiastic laboratory technician who will be part of an interdisciplinary team of scientists working on leadXpro proprietary as well as partnered projects within a highly collaborative international environment. She/he will perform membrane protein expression and purification in quantities that enable structural and biophysical studies.

The successful candidate will be expected to work within a dynamic team that values transparency, integrity, reliability and a passion for science to create benefits for the patients. Key duties include:

  • Performing scientific research under guidance of an experienced supervisor
  • Maintaining cultures of insect and mammalian cells and generation of baculoviruses
  • Screening of expression conditions using fluorescence-based techniques and Western blot
  • Optimization and upscaling of recombinant protein expression
  • Purification of membrane proteins using chromatography methods (affinity, ion exchange and size exclusion chromatography)
  • Monitoring of protein quality and purity using fluorescence-size exclusion chromatography and SDS-PAGE
  • Maintenance of laboratory records and participation in data analysis
  • Taking part in laboratory organization and maintenance of supplies and equipment

Requirements

Applicants should preferably have an apprenticeship education or equivalent (B.Sc.). in biochemistry, molecular biology, biotechnology or a related discipline. Hands-on experience with protein expression, purification as well as standard protein analytical techniques is expected. Previous experience with membrane protein biochemistry would be a plus. Excellent communication skills and fluency in English is essential.

Contact and Address

If you are interested to join the team, please send your C.V. with the keyword “Technician Protein Expression and Purification” in the subject line per email to: infoleadXpro.com
The deadline for the application is March 10th, 2020.

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In your application, please refer to myScience.be and reference JobID 2969.

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