Postdoctoral researcher Medicinal chemistry and proline-specific proteases

WorkplaceAntwerpen, Flemish Region, Belgium
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Department: Department of Pharmaceutical Sciences
Regime Full-time

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The University of Antwerp is a dynamic, forward-thinking, European university. We offer an innovative academic education to more than 20000 students, conduct pioneering scientific research and play an important service-providing role in society. We are one of the largest, most international and most innovative employers in the region. With more than 6000 employees from 100 different countries, we are helping to build tomorrow's world every day. Through top scientific research, we push back boundaries and set a course for the future – a future that you can help to shape.

The Faculty of Pharmaceutical, Biomedical and Veterinary Sciences at the University of Antwerp is seeking to fill a full-time (100%) vacancies in the Department of Pharmaceutical Sciences for a postdoctoral researcher in the area of Medicinal chemistry and proline-specific proteases.


  • You will be working in the research group Medicinal Chemistry (UAMC) on lead optimization of inhibitors and activity-based probes for proline-specific proteases. These enzymes are drug targets in, among others, oncology.
  • Background research topic: UAMC has longstanding expertise with developing small molecule ligands (inhibitors, activity-based probes) for proline-specific proteases that are involved in human disease. In this project you will develop ligands for proline selective proteases that have key roles in tumor biology. Developed ligands will be evaluated for target affinity and selectivity in collaboration with the Medical Biochemistry group at University of Antwerp. Promising molecules will be evaluated in in vitro and, eventually, in vivo models of cancer.
  • Research topic for this postdoc position: Synthetic lead optimization of inhibitors and activity-based Probes for proline-specific proteases.
  • Next to experimental research, you will write project reports for your supervisor on a regular basis, write scientific papers and support grant writing.


  • You hold a doctoral degree (PhD) in Chemistry, Pharmaceutical Sciences or Engineering Sciences with experience in synthetic organic chemistry and/or medicinal chemistry
  • Expertise in lead optimization process is an asset
  • You did not reside, study or work in Belgium for more than 24 months in the 3 years immediately prior to the recruitment date (eligibility rule for postdoc with a subsidy)
  • Your academic qualities comply with the requirements stipulated in the university research policies .
  • You co-supervise PhD candidates
  • You are quality-oriented, conscientious, creative and cooperative.
  • You have strong communication skills.
  • You are fluent in academic English (speaking and writing)

What we offer

  • An appointment as a postdoctoral researcher for a period of one year, eventually renewable for one more year.
  • The date of appointment: as soon as possible.
  • Your monthly scholarship amount is calculated according to the scholarship amounts for postdoctoral scholarship holders on the pay scales for Contract Research Staff (Dutch: Bijzonder Academisch Personeel, BAP).
  • You will receive ecocheques, Internet-connectivity allowance and a bicycle allowance or a full reimbursement of public transport costs for commuting.
  • You will do most of your work at Campus Drie Eiken in a dynamic and stimulating working environment.
  • Find out more about working at the University of Antwerp here .

Want to apply?

  • You can apply for this vacancy through the University of Antwerp’s online job application platform up to and including October 2nd, 2022(by midnight Brussels time). Click on the 'Apply' button, complete the online application form and be sure to include the following attachments: a motivation letter and your CV.
  • A pre-selection will be made from amongst the submitted applications.
  • The remainder of the selection procedure is specific to the position and will be determined by the selection panel.
  • If you have any questions about the online application form, please check the please check the frequently asked questions or send an email to . For questions about the profile and the description of duties, please contact Prof. Pieter Van der Veken ( )

The University of Antwerp received the European Commission’s HR Excellence in Research Award for its HR policy. We are a sustainable, family-friendly organisation which invests in its employees’ growth. We encourage diversity and attach great importance to an inclusive working environment and equal opportunities, regardless of gender identity, disability, race, ethnicity, religion or belief, sexual orientation or age. We encourage people from diverse backgrounds and with diverse characteristics to apply.

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In your application, please refer to and reference JobID 5699.