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Life Sciences - Health - 26.11.2019
A protein tag to study the immune system
Researchers from VIB-Ghent Universitiy Center for Medical Biotechnology and other collaborators, developed a novel approach to better understand a basic defense mechanism of our immune system. Central is ISG15, a small protein with a role in the immune system. With the newly developed method, scientists can now identify and study proteins tagged with ISG15, allowing them to unravel its many functions in fighting disease, potentially leading to novel antimicrobial drugs.

Health - Life Sciences - 19.11.2019
KU Leuven researchers receive 3 million dollars to fight Crohn’s disease
Why do some patients with Crohn's disease still suffer from abdominal pain, even when their treatment is successful? With funding from the Helmsley Charitable Trust, researchers from Belgium and Sweden will spend the next three years examining the underlying mechanisms of this pain. Approximately 3 out of 1000 people have Crohn's disease, which is characterised by intestinal inflammation.

Life Sciences - Health - 29.10.2019
Electrodes to study how our brain recognises objects
Electrodes to study how our brain recognises objects
For the first time ever, researchers from KU Leuven have carried out tests on human brains in the area that is responsible for our vision. This research method is unique. The results have been published in PLOS Biology . To gain a better understanding of the human brain, researchers can rely on several methods.

Health - 22.10.2019
Anti-arthritis drug also stops tuberculosis bacillus from multiplying in blood stem cells
Immunologist Johan Van Weyenbergh (KU Leuven) and his Belgian-Brazilian colleagues have shown that a drug used to fight arthritis also stops the process that allows the tuberculosis bacillus to infect and hijack blood stem cells. Tuberculosis (TB) may affect any part of the body, but the spread of the disease might start in the bone marrow.

Life Sciences - Health - 14.10.2019
The electric switches in our brain need lipids
Our brain cells, and more specifically the channel proteins in the cell wall, need lipids - or fat - to function properly. These are the findings of an international study led by the Laboratory of Structural Neurobiology at KU Leuven. The researchers identified the structure of these proteins in the presence of a lipid molecule at the atomic level for the first time.

Life Sciences - Health - 14.10.2019
Stem cell researchers identify possible mechanism of neurocognitive problems in Duchenne muscular dystrophy
Research at KU Leuven suggests a cause for the neurodevelopmental disturbances experienced by a third of patients with Duchenne muscular dystrophy. The discovery suggests possible underlying mechanisms of these problems, which appear targetable by therapeutic interventions in a cellular model.  Duchenne muscular dystrophy (DMD) is an inherited neuromuscular disorder in which the muscles, including the heart and respiratory muscles, progressively become weaker.

Health - Pharmacology - 19.09.2019
One step closer to treating and preventing stomach flu thanks to new research model
One step closer to treating and preventing stomach flu thanks to new research model
Researchers at KU Leuven have developed a new research model to grow and study the human variant of the norovirus. The virus could thus far only be studied through a variant that occurs in mice. The new model, that is described in the journal PLOS Pathogens, should allow researchers to develop a treatment for stomach flu.

Pharmacology - Health - 11.09.2019
Can a DNA construction kit replace expensive antibody medication?
Researchers at KU Leuven in Belgium have developed a technique to make sheep produce new antibodies simply by injecting the DNA building blocks. This approach is much cheaper and more efficient than producing antibodies industrially and administering them afterwards. The study in animals with a similar size as humans brings us a step closer to the clinical use of antibody gene therapy.

Life Sciences - Health - 09.08.2019
Researchers use CRISPR/Cas to repair two mutations of the cystic fibrosis gene
Biomedical scientists at KU Leuven and the University of Trento have used gene correction to fix two mutations that cause cystic fibrosis. The breakthrough involved a petri dish with 3D cell structures, or organoids, from cystic fibrosis patients. Cystic fibrosis is the most common genetic disorder in Belgium.

Health - 07.08.2019
24-hour blood pressure monitoring is the best way to predict cardiovascular diseases
An international study led by Professor Jan Staessen and Professor Zhen-Yu Zhang has shown that 24-hour blood pressure monitoring, including when the patient is asleep, has the highest predictive accuracy for cardiovascular diseases.  An international consortium followed 11,135 individuals for up to 14 years.

Health - Pharmacology - 01.08.2019
Endometrial diseases can be imitated in a lab dish
Biomedical researchers at KU Leuven have found a new way to study endometrial diseases such as endometriosis and cancer. They were able to grow three-dimensional cell structures from diseased tissue of patients. The biobank can be used to unravel the disorders and test drugs. Diseases of the endometrium are an important cause of infertility.

Health - Pharmacology - 03.07.2019
Paediatric cancers: towards more targeted therapy
Chemotherapy attacks cancer cells but also healthy cells. In children, it often causes irreversible damage that can impact their adult lives. UCLouvain researcher Anabelle Decottignies has found a possible strategy for killing cancer cells, especially in children, without affecting healthy cells , as reported in the scientific journal Molecular Cell .

Health - Life Sciences - 01.07.2019
A bacteria likely to reduce the cardiovascular risks of 1 in 2 people
Patrice Cani, professor at UCLouvain, and his team conducted the first pilot study in humans to observe the impact of the bacteria Akkermansia (ingestion for 3 months), particularly on the reduction of cardiovascular risk factors. The results are published in the scientific journal Nature Medicine .

Pharmacology - Health - 12.06.2019
New vulnerability found in viruses may help develop cure for the common cold
A team of researchers led by KU Leuven virologist Johan Neyts have discovered a new feature of so-called picornaviruses that may allow for the development of new antiviral medications for the common cold, polio, and other illnesses. Picornaviruses include rhinoviruses and enteroviruses. Rhinoviruses cause millions of cases of upper respiratory infections ("colds") yearly and contribute to asthma, and enteroviruses are responsible for millions of infections including cases such as meningitis, encephalitis and polio.

Life Sciences - Health - 03.06.2019
Towards a new era of small animal imaging research
A collaborative study between the University of Antwerp and McGill University allows PET scanning on animals without the use of anesthesia. Have you ever spent half an hour trying to take the best photo of your pets but they won't stay still in the perfect angle? This is also true for small animal imaging research using positron emission tomography (PET).

Health - Life Sciences - 25.04.2019
New genome analytics platform makes clinical genomics affordable for daily use in hospital
Imec, UZ Leuven, KU Leuven, Ghent University, Agilent, Western Digital and BlueBee develop unique hybrid cloud platform for fast and cost-efficient whole genome sequencing and analysis. Today, on the occasion of the international DNA day, imec, a world-leading research and innovation hub in nanoelectronics and digital technologies, and its partners revealed their Genome Analytics Platform (GAP) platform, a unique platform that can perform a full genome analysis of 48 samples in only 48 hours and at an acceptable cost.

Life Sciences - Health - 01.04.2019
Artificial intelligence sheds new light on cell developmental dynamics
What happens inside a cell when it is activated, changing, or responding to variations in its environment? Researchers from the VIB-Ghent University Center for Inflammation Research have developed a map of how to best model these cellular dynamics. Their work not only highlights the outstanding challenges of tracking cells throughout their growth and lifetime, but also pioneers new ways of evaluating computational biology methods that aim to do this.

Life Sciences - Health - 14.03.2019
New approach to stroke treatment could minimize brain damage
A new treatment for a common type of stroke may soon be possible, thanks to a discovery by an international team of researchers. In a study published today in the Journal of Experimental Medicine , researchers successfully used a new approach that significantly minimized brain damage caused by stroke in mouse models.

Life Sciences - Health - 04.02.2019
Gut bacteria may influence your mental health
Researchers at VIB-KU Leuven have identified several gut bacteria that may be linked to depression. Their findings provide further evidence that our intestinal bacteria produce substances with a potential impact on our mental health. Jeroen Raes and his team at VIB-KU Leuven examined the faeces of 1,054 participants in the Flemish Gut Flora Project and combined this information with diagnoses of depression in the same group.

Life Sciences - Health - 28.01.2019
"Stop, do not eat fat anymore!"
During fat ingestion , if everything works in our body, an enzyme from the intestine transmits to the brain (through the production of molecules) the message "stop, I am not hungry anymore". This gut-brain axis maintains a balanced food intake. Researchers from the UCLouvain were able to target this enzyme.

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