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Pharmacology - Health - 23.07.2021
Important factor in transplant rejection identified
KU Leuven researchers have revealed the importance of a newly identified mechanism of kidney transplant rejection. These results could increase the chances of a successful transplantation in the future.  Each year, about 500 people in our country undergo a kidney transplant. 15 to 20% of these patients experience rejection symptoms.

Health - Pharmacology - 22.07.2021
Antibiotics may help to treat melanoma
Antibiotics may help to treat melanoma
Some antibiotics appear to be effective against a form of skin cancer known as melanoma. KU Leuven researchers examined the effect of these antibiotics on patient-derived tumours in mice. Some antibiotics appear to be effective against a form of skin cancer known as melanoma. KU Leuven researchers examined the effect of these antibiotics on patient-derived tumours in mice.

Health - Pharmacology - 25.06.2021
Clinical trial with virtual patients shows great potential
Clinical trial with virtual patients shows great potential
A study involving virtual instead of real patients was as effective as traditional clinical trials in evaluating a medical device used to treat brain aneurysms, according to researchers from the University of Leeds and KU Leuven. Furthermore, the 'virtual' approach required far less time and money. A study involving virtual instead of real patients was as effective as traditional clinical trials in evaluating a medical device used to treat brain aneurysms, according to researchers from the University of Leeds and KU Leuven.

Health - Pharmacology - 19.05.2021
Cardiologist calls for increased prevention of high blood pressure
Cardiologist calls for increased prevention of high blood pressure
Wednesday, May 19, 2021 — The annual World Hypertension Day on 17 May prompted the publication of a review article on hypertension that appears today in the leading journal The Lancet. In this article, Prof Sofie Brouwers, OLV Ziekenhuis Aalst and Vrije Universiteit Brussel, and her colleagues present the current state of affairs regarding arterial hypertension.

Health - Pharmacology - 01.04.2021
VUB provides breakthrough in chronic pain management
Thursday, April 1, 2021 — An international team of experts has provided a breakthrough in the study of chronic pain in rheumatoid arthritis patients. "We discovered that hypersensitivity is often the cause for all kinds of chronic pain. Personalised treatment tailored to the patient offers the solution here,' says VUB professor Jo Nijs, who is in charge of the project.

Health - Pharmacology - 30.03.2021
VIB/VUB-team map immune cells in aggressive brain tumor
Human glioblastoma tumors are aggressive hard-to-treat brain cancers that have a high unmet need for new treatment options. A team of researchers led by Prof. Kiavash Movahedi and Prof. Jo Van Ginderachter (VIB-VUB), in collaboration with colleagues from VIB, VUB, and KU Leuven, have mapped the immune landscape in these glioblastoma tumors.

Health - Pharmacology - 08.02.2021
Scientists switch on tissue repair in inflammatory bowel disease
A method that instructs immune system cells to help repair damaged tissues in the intestine has been developed by researchers at KU Leuven and Seoul National University. This opens the way for more effective treatment of inflammatory bowel disease, including ulcerative colitis and Crohn's disease. The study was carried out on humans and mice.

Health - Pharmacology - 13.01.2021
Mechanism that causes irritable bowel syndrome
KU Leuven researchers have identified the biological mechanism that explains why some people experience abdominal pain when they eat certain foods. The finding paves the way for more efficient treatment of irritable bowel syndrome and other food intolerances. Up to 20% of the world's population suffers from irritable bowel syndrome (IBS), which causes stomach pain or severe discomfort after eating.

Health - Pharmacology - 01.12.2020
Update: KU Leuven Covid-19 vaccine study published in Nature
Update: KU Leuven Covid-19 vaccine study published in Nature
Today, virologists at the KU Leuven Rega Institute published the results of their pre-clinical study into a Covid-19 vaccine candidate in  Nature . Their paper builds on a preprint that the team shared on bioRxiv earlier this year, and that  we reported on. The vaccine candidate is based on the yellow fever vaccine and thus also protects against yellow fever.

Health - Pharmacology - 26.10.2020
’Preventive malaria treatment improves children’s performance at school’
UAntwerp involved in large-scale international research to be published in The Lancet. School-aged children who are given anti-malaria drugs preventively are only half as likely to catch the disease. And that's not all: their risk of anaemia decreases by 15%, and their school performance improves. All this has been demonstrated by international research in which the University of Antwerp was also involved.

Health - Pharmacology - 09.10.2020
Hydroxychloroquine does not counter SARS-CoV-2 in hamsters, but a high dose of favipiravir does
Hydroxychloroquine does not counter SARS-CoV-2 in hamsters, but a high dose of favipiravir does
Virologists at the Rega Institute have shown that the anti-malaria drug hydroxychloroquine does not limit SARS-CoV-2 coronavirus replication in hamsters. A high dose of the anti-flu drug favipiravir, by contrast, has an antiviral effect in the hamsters.

Health - Pharmacology - 28.07.2020
ExeVir Bio to Accelerate Development of New Treatment Conferring Broad Protection Against Covid-19
ExeVir Bio, a technology platform with potential to generate robust antiviral therapies. ExeVir Bio announces today a first closing of a EUR23 million Series A financing led by Fund+, with the participation of VIB, UCB Ventures, the Belgian Federal Government via SFPI-FPIM, V-Bio Ventures and several Belgian family offices.

Pharmacology - Health - 09.07.2020
KU Leuven virologists select vaccine candidate for clinical trials
KU Leuven virologists select vaccine candidate for clinical trials
Virologists at the Rega Institute at KU Leuven (Belgium) have developed a vaccine candidate that protects hamsters from infection with the SARS-CoV-2 coronavirus. Theirs is one of the first vaccine candidates that is proven to protect lab animals from infection. The team aims to start clinical trials next Winter.

Pharmacology - Health - 03.07.2020
Popular chemotherapy drug may be less effective in overweight and obese women
Popular chemotherapy drug may be less effective in overweight and obese women
Breast cancer patients who are overweight or obese might benefit less from treatment with docetaxel, a common chemotherapy drug, than lean patients. An international team of researchers based this conclusion on a retrospective analysis of data from a large clinical trial. Their study was published in the Journal of Clinical Oncology .

Health - Pharmacology - 07.06.2020
Researchers against Covid-19
They did not sit back during the lockdown! As scientists worldwide, the UNamur researchers were in the battle against Covid-19 since the beginning of the crisis. Their expertise bore around 20 research projects, often in collaboration with other Belgian or foreign universities. Thanks to their initiatives and work, society becomes aware of the importance of research and the numerous disciplines involved when fighting a pandemic.

Pharmacology - Economics / Business - 04.03.2020
Average cost of developing a new drug could be up to $1.5 billion less than pharmaceutical industry claims
Average cost of developing a new drug could be up to $1.5 billion less than pharmaceutical industry claims
The costs of bringing a new drug to market may be lower than has been previously claimed by the pharmaceutical industry, according to a study published today (Tuesday March 3, 2020) in the journal JAMA.

Pharmacology - 19.02.2020
Antiviral activity of chloroquine against coronaviruses discovered at KU Leuven in 2004
Chloroquine, an antimalarial medicine that has been on the international market since 1934, proves to be active against the novel SARS coronavirus type 2 (COVID-19).

Pharmacology - Health - 10.02.2020
VIB works on antiviral drug aimed to halt coronavirus outbreak
The lab of professor Xavier Saelens (VIB-Ghent University) is quickly mobilizing to try to find a treatment for the viral infection caused by the corona virus. Since the coronavirus (2019-nCoV) outbreak was reported by China in December 2019, the number of confirmed cases of the virus is increasing rapidly, with cases now reported in 28 countries.

Health - Pharmacology - 23.01.2020
Preventing metastasis by stopping cancer cells from making fat
In brief  (18 seconds of reading): Olivier Feron , a UCLouvain researcher, studies how cancer spreads through the body via metastasis His major discovery was that cancer cells multiply by using lipids as food. His latest discovery, published in the scientific , is that lipid storage promotes cancer invasiveness A new drug currently being tested to treat obesity may also help fight metastasis Olivier Feron, a researcher at the University of Louvain (UCLouvain) Institute of Experimental and Clinical Research, seeks to understand how metastases form from a tumour.

Health - Pharmacology - 21.01.2020
Leuven researchers present technique to grow tissue implants for bone defects
Researchers from KU Leuven and University Hospitals Leuven have managed to engineer living implants in the lab by mimicking how bone tissue is created in an embryo. The technology paves the way for bone-regenerating tissue implants created on an industrial scale using 3D bioprinting. The researchers expect the first living implants to be available to patients in four years.

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